PITX3 genotype and risk of dementia in Parkinson's disease: A population-based study.

doi:10.1016/j.jns.2017.08.3259

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Article

PITX3 genotype and risk of dementia in Parkinson's disease: A population-based study.

Journal of the neurological sciences - 15 Oct 2017

Bäckström David, Domellöf Magdalena Eriksson, Granåsen Gabriel, Linder Jan, Mayans Sofia, Elgh Eva, Mo Susanna Jakobson, Forsgren Lars

Abstract excerpt

Dementia is a devastating manifestation of Parkinson's disease (PD). This study investigates whether a common polymorphism in the PITX3 gene (rs2281983), which is of importance for the function of dopaminergic neurons, affects the risk of developing dementia in PD and whether it affects dopamine transporter (DAT) uptake. We PITX3 genotyped 133 patients with new-onset, idiopathic PD, participating in a...

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PMID: 28991698
DOI: 10.1016/j.jns.2017.08.3259

Genes

PITX3
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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