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Article

BRAF V600E mutation is a significant prognosticator of the tumour regrowth rate in brainstem gangliogliomas.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Dec 2017

Chen Xin, Pan Changcun, Zhang Peng, Xu Cheng, Sun Yu, Yu Hai, Wu Yuliang, Geng Yibo, Zuo Pengcheng, Wu Zhen, Zhang Junting, Zhang Liwei

Abstract excerpt

BRAF V600E mutations are progression factors in paediatric low-grade gliomas. Furthermore, a high percentage of paediatric brainstem gangliogliomas have BRAF V600E mutations. However, their clinical significance, including possible connections between the biomarkers and ganglioglioma's clinical features, especially a brainstem counterpart, is unclear. To identify potential molecular features predictive of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

Source

Identifiers

PMID: 28986151
DOI: 10.1016/j.jocn.2017.09.014

Genes

BRAF
IDH1
IDH2
MGMT
TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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