Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Shared genetic influence on frailty and chronic widespread pain: a study from TwinsUK.

Age and ageing - 1 Jan 2018

Livshits Gregory, Ni Lochlainn Mary, Malkin Ida, Bowyer Ruth, Verdi Serena, Steves Claire J, Williams Frances M K

Abstract excerpt

Introduction: frailty is an increased vulnerability to adverse health outcomes, across multiple physiological systems, with both environmental and genetic drivers. The two most commonly used measures are Rockwood's frailty index (FI) and Fried's frailty phenotype (FP). Material and methods: the present study included 3626 individuals from the TwinsUK Adult Twin Registry. We used the classical twin model to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Pain
Share to Frail Elderly
Share to Frailty

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Geriatric Assessment

Share to Heredity

Share to Pain Measurement

Share to Twins, Dizygotic

Share to Twins, Monozygotic

Source

Open in PubMed Open full text

Identifiers

PMID: 28985290
DOI: 10.1093/ageing/afx122
PMCID: PMC5860041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Shared genetic influence on frailty and chronic widespread pain: a study from TwinsUK.PMID 28985290Read ↗

A Genome-Wide Association Study of the Frailty Index Highlights Synaptic Pathways in AgingSemantic proximity Read ↗

A genome‐wide association study of the frailty index highlights brain pathways in ageingSemantic proximity Read ↗

A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways.Semantic proximity Read ↗

Association between pain and the frailty phenotype in older men: longitudinal results from the Concord Health and Ageing in Men Project (CHAMP).Semantic proximity Read ↗

Frailty Index associates with GRIN2B in two representative samples from the United States and the United KingdomSemantic proximity Read ↗

Uncovering the multivariate genetic architecture of frailty with genomic structural equation modellingSemantic proximity Read ↗

The phenotypic and genotypic association of grip strength with frailty, physical performance and functional limitations over time in older adults.Semantic proximity Read ↗

Incorporating Persistent Pain in Phenotypic Frailty Measurement and Prediction of Adverse Health Outcomes.Semantic proximity Read ↗

Frailty and the risk of dementia: is the association explained by shared environmental and genetic factors?Semantic proximity Read ↗

Predicting factors associated with frailty in aged patients with bone-arthrosis pain in the clinic.Semantic proximity Read ↗

Frailty and fracture, disability, and falls: a multiple country study from the global longitudinal study of osteoporosis in women.Semantic proximity Read ↗

Exploring the causal association between frailty index with the common types of arthritis: a Mendelian randomization analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.