Article
The 9p21 Rs 1333040 polymorphism is associated with coronary microvascular obstruction in ST-segment elevation myocardial infarction treated by primary angioplasty.
European heart journal. Acute cardiovascular care - 1 Dec 2019
Fracassi Francesco, Niccoli Giampaolo, Vetrugno Vincenzo, Cauteruccio Michele, Buffon Antonino, Gatto Ilaria, Giarretta Igor, Tondi Paolo, Pola Roberto, Crea Filippo
Abstract excerpt
BACKGROUND: Microvascular obstruction (MVO) after primary percutaneous coronary intervention (pPCI) leads to higher incidence of both early and late complications. A number of single nucleotide polymorphisms in 9p21 chromosome have been shown to affect angiogenesis in response to ischaemia. In particular, Rs1333040 with its three genotypic vriants C/C, T/C and T/T might influence the occurrence of MVO after pPCI....
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