Article
PCSK9 gene variations in the clinical setting of premature cardiovascular disease: A critical appraisal.
International journal of cardiology - 15 Oct 2024
Lorca Rebeca, Aparicio Andrea, Gutiérrez Luis, Álvarez-Velasco Rut, González-Urbistondo Francisco, Pascual Isaac, Gómez Juan, Vazquez-Coto Daniel, Garcia-Lago Claudia, Avanzas Pablo, Coto Eliecer
Abstract excerpt
INTRODUCTION: Information about PCSK9 gene variations and its association with cardiovascular (CV) disease is controversial. We aimed to evaluate 3 reported polymorphisms in PSCK9 in a cohort of young patients with myocardial infarction with ST segment elevation (STEMI). METHODS: Retrospective study of consecutive patients with premature STEMI (2018-2023). 216 patients with STEMI due atherothrombotic coronary...
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