Article
GTF2I Mutations Are Common in Thymic Epithelial Tumors But Not in Hematological Malignancies.
Anticancer research - 1 Oct 2017
Tarrini Giulia, Ciabatti Elena, Pacini Simone, Galimberti Sara, Petrini Iacopo
Abstract excerpt
BACKGROUND: Mutation of general transcription factor IIi (GTF2I) (chromosome 7 c.74146970T>A) is common in thymic epithelial tumors and is a candidate driver aberration for cancer growth. To our knowledge, this mutation has not been described in other diseases. We evaluated the presence of GTF2I mutation in hematological malignancies. MATERIALS AND METHODS: We sequenced samples from 31 patients with acute...
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