Article
Rapid pathogen-specific phenotypic antibiotic susceptibility testing using digital LAMP quantification in clinical samples.
Science translational medicine - 4 Oct 2017
Schoepp Nathan G, Schlappi Travis S, Curtis Matthew S, Butkovich Slava S, Miller Shelley, Humphries Romney M, Ismagilov Rustem F
Abstract excerpt
Rapid antimicrobial susceptibility testing (AST) is urgently needed for informing treatment decisions and preventing the spread of antimicrobial resistance resulting from the misuse and overuse of antibiotics. To date, no phenotypic AST exists that can be performed within a single patient visit (30 min) directly from clinical samples. We show that AST results can be obtained by using digital nucleic acid...
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