Novel CRISPR-Cas13 Biosensor for Real-Time Detection of Antimicrobial Resistance Genes in Environmental Microbiomes

Abstract excerpt

<h4>Background: </h4> The emergence and spread of antimicrobial resistance (AMR) genes in environmental microbiomes pose a critical threat to global health security. Current detection methods are time-consuming and often lack the sensitivity required for early environmental surveillance. Methods We developed a novel CRISPR-Cas13a-based biosensor system coupled with isothermal amplification for rapid, field-deplo...

Topics

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• Advanced biosensing and bioanalysis techniques
• Antimicrobial Resistance in Staphylococcus
• Biosensors and Analytical Detection
• CRISPR and Genetic Engineering
• SARS-CoV-2 and COVID-19 Research
• SARS-CoV-2 detection and testing

Identifiers and source

Literature Corpus work

737103a0-551a-5fc6-b117-c3453c8851ac

DOI

10.1099/acmi.0.001081.v2