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Article

MiR-125a Is a critical modulator for neutrophil development

4 Oct 2017

Abstract excerpt

MicroRNAs are universal post-transcriptional regulators in genomes. They have the ability of buffering gene expressional programs, contributing to robustness of biological systems and playing important roles in development, physiology and diseases. Here, we identified a microRNA, miR-125a, as a positive regulator of granulopoiesis. MiR125a knockout mice show reduced infiltration of neutrophils in the lung and...

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PMID: 28976973
DOI: 10.1371/journal.pgen.1007027

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