Article
SLCO1A2, SLCO1B1 and SLCO2B1 polymorphisms influences chloroquine and primaquine treatment in Plasmodium vivax malaria.
Pharmacogenomics - 1 Oct 2017
Sortica Vinicius A, Lindenau Juliana D, Cunha Maristela G, O Ohnishi Maria Deise, R Ventura Ana Maria, Ribeiro-Dos-Santos Ândrea Kc, Santos Sidney Eb, Guimarães Luciano Sp, Hutz Mara H
Abstract excerpt
AIM: The association of transporters gene polymorphisms with chloroquine/primaquine malaria treatment response was investigated in a Brazilian population. PATIENTS & METHODS: Totally, 164 Plasmodium vivax malaria infected patients were included. Generalized estimating equations were performed to determine gene influences on parasitemia and/or gametocytemia clearance over treatment time. RESULTS: Significant...
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