Article
Prevalence of metabolic syndrome in obese Chilean children and association with gene variants of the leptin-melanocortin system.
Journal of pediatric endocrinology & metabolism : JPEM - 1 Jan 2013
Suazo José, Hodgson María Isabel, Obregón Ana María, Valladares Macarena, Weisstaub Gerardo, Amador Paola, Santos José Luis
Abstract excerpt
Metabolic syndrome (MS) related to adult type 2 diabetes mellitus and cardiovascular disease is prevalent among obese children/adolescents. Genetic variants of the leptin-melanocortin system have been associated with components of MS. The aim of our study is to estimate the prevalence of MS (according to Cook's criteria) in a Chilean cross-sectional sample of 259 obese children (47.1% girls, aged 6-12 years), and...
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