Article
Insights into a Pyruvate Sensing and Uptake System in Vibrio campbellii and Its Importance for Virulence.
Journal of bacteriology - 23 Sept 2021
Göing Stephanie, Gasperotti Ana Florencia, Yang Qian, Defoirdt Tom, Jung Kirsten
Abstract excerpt
Pyruvate is a key metabolite in living cells and has been shown to play a crucial role in the virulence of several bacterial pathogens. The bioluminescent Vibrio campbellii, a severe infectious burden for marine aquaculture, excretes extraordinarily large amounts of pyruvate during growth and rapidly retrieves it by an as-yet-unknown mechanism. We have now identified the responsible pyruvate transporter, here...
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