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Article

A Single-Cell View of the BtsSR/YpdAB Pyruvate Sensing Network in Escherichia coli and Its Biological Relevance.

Journal of bacteriology - 1 Jan 2018

Vilhena Cláudia, Kaganovitch Eugen, Shin Jae Yen, Grünberger Alexander, Behr Stefan, Kristoficova Ivica, Brameyer Sophie, Kohlheyer Dietrich, Jung Kirsten

Abstract excerpt

Fluctuating environments and individual physiological diversity force bacteria to constantly adapt and optimize the uptake of substrates. We focus here on two very similar two-component systems (TCSs) of Escherichia coli belonging to the LytS/LytTR family: BtsS/BtsR (formerly YehU/YehT) and YpdA/YpdB. Both TCSs respond to extracellular pyruvate, albeit with different affinities, typically during postexponential...

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Identifiers

PMID: 29038258
DOI: 10.1128/JB.00536-17
PMCID: PMC5717152

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