Article
The structural basis for signal promiscuity in a bacterial chemoreceptor.
The FEBS journal - 1 Apr 2021
Gavira José Antonio, Matilla Miguel A, Fernández Matilde, Krell Tino
Abstract excerpt
Signalling through chemosensory pathways is typically initiated by the binding of signal molecules to the chemoreceptor ligand binding domain (LBD). The PcaY_PP chemoreceptor from Pseudomonas putida KT2440 is characterized by an unusually broad signal range, and minimal requisites for signal binding are the presence of a C6-membered ring and that of a carboxyl group. Previous studies have shown that only some of...
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