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Article

Association of Endothelial Nitric Oxide Synthase Gene Polymorphism with Susceptibility and Nephritis Development of Henoch-Schönlein Purpura in Chinese Han Children.

Genetic testing and molecular biomarkers - 1 Jun 2017

Wang Ailing, Wang Aili, Xiao Yanfeng, Wang Jingjing, Xu Erdi

Abstract excerpt

OBJECTIVE: Henoch-Schönlein purpura (HSP) is the most common form of systemic small-vessel vasculitis in children. Previous studies suggested endothelial nitric oxide synthase (eNOS) plays an important role in the pathogenesis and clinical manifestations of HSP. This study aimed to investigate the potential association between 10 single-nucleotide polymorphisms (SNPs) within the eNOS gene and HSP risk and...

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PMID: 28409662
DOI: 10.1089/gtmb.2016.0213

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