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Article

Effect of β-lactamase production and β-lactam instability on MIC testing results for Mycobacterium abscessus.

The Journal of antimicrobial chemotherapy - 1 Nov 2017

Rominski Anna, Schulthess Bettina, Müller Daniel M, Keller Peter M, Sander Peter

Abstract excerpt

OBJECTIVES: Limited treatment options available for Mycobacterium abscessus infections include the parenteral β-lactam antibiotics cefoxitin and imipenem, which show moderate in vitro activity. Other β-lactam antibiotics (except meropenem) have no considerable in vitro activity, due to their rapid hydrolysis by a broad-spectrum β-lactamase (Bla_Mab). We here addressed the impact of β-lactamase production and...

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Identifiers

PMID: 28961987
DOI: 10.1093/jac/dkx284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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