Article
Population Structure and Local Adaptation of MAC Lung Disease Agent Mycobacterium avium subsp. hominissuis.
Genome biology and evolution - 1 Sept 2017
Yano Hirokazu, Iwamoto Tomotada, Nishiuchi Yukiko, Nakajima Chie, Starkova Daria A, Mokrousov Igor, Narvskaya Olga, Yoshida Shiomi, Arikawa Kentaro, Nakanishi Noriko, Osaki Ken, Nakagawa Ichiro, Ato Manabu, Suzuki Yasuhiko, Maruyama Fumito
Abstract excerpt
Mycobacterium avium subsp. hominissuis (MAH) is one of the most common nontuberculous mycobacterial species responsible for chronic lung disease in humans. Despite increasing worldwide incidence, little is known about the genetic mechanisms behind the population evolution of MAH. To elucidate the local adaptation mechanisms of MAH, we assessed genetic population structure, the mutual homologous recombination, and...
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