Article
Comparative genome analysis of Mycobacterium avium revealed genetic diversity in strains that cause pulmonary and disseminated disease.
PloS one - 1 Jan 2013
Uchiya Kei-ichi, Takahashi Hiroyasu, Yagi Tetsuya, Moriyama Makoto, Inagaki Takayuki, Ichikawa Kazuya, Nakagawa Taku, Nikai Toshiaki, Ogawa Kenji
Abstract excerpt
Mycobacterium avium complex (MAC) infection causes disseminated disease in immunocompromised hosts, such as human immunodeficiency virus (HIV)-positive patients, and pulmonary disease in persons without systemic immunosuppression, which has been increasing in many countries. In Japan, the incidence of pulmonary MAC disease caused by M. avium is about 7 times higher than that caused by M. intracellulare. To...
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