Article
K13 Propeller Alleles, mdr1 Polymorphism, and Drug Effectiveness at Day 3 after Artemether-Lumefantrine Treatment for Plasmodium falciparum Malaria in Colombia, 2014-2015.
Antimicrobial agents and chemotherapy - 1 Dec 2017
Montenegro Madeline, Neal Aaron T, Posada Maritza, De Las Salas Briegel, Lopera-Mesa Tatiana M, Fairhurst Rick M, Tobon-Castaño Alberto
Abstract excerpt
High treatment failure rates for Plasmodium falciparum malaria have been reported in Colombia for chloroquine, amodiaquine, and sulfadoxine-pyrimethamine. Artemisinin combination therapies were introduced in 2006 in Colombia, where artemether-lumefantrine (AL) is currently used to treat uncomplicated P. falciparum malaria. Artemisinin (ART) resistance was initially observed in Southeast Asia as an increased...
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