Expression of TFH Markers and Detection of RHOA p.G17V and IDH2 p.R172K/S Mutations in Cutaneous Localizations of Angioimmunoblastic T-Cell Lymphomas.

doi:10.1097/PAS.0000000000000956

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Article

Expression of TFH Markers and Detection of RHOA p.G17V and IDH2 p.R172K/S Mutations in Cutaneous Localizations of Angioimmunoblastic T-Cell Lymphomas.

The American journal of surgical pathology - 1 Dec 2017

Leclaire Alirkilicarslan Ariane, Dupuy Aurélie, Pujals Anaïs, Parrens Marie, Vergier Béatrice, Robson Alistair, Delfau-Larue Marie-Hélène, Ingen-Housz-Oro Saskia, Chosidow Olivier, Haioun Corinne, Beylot-Barry Marie, Merlio Jean-Philippe, Copie-Bergman Christiane, Gaulard Philippe, Ortonne Nicolas

Abstract excerpt

Skin biopsies of 41 angioimmunoblastic T-cell lymphoma patients were retrospectively analyzed for the expression of follicular helper T-cell (TFH) markers, Epstein-Barr virus (EBV), and the presence of RHOA (p.G17V) and IDH2 (p.R172K/S) mutations using allele-specific polymerase chain reaction. We categorized cases into 4 distinctive patterns: (1) low-density lymphocytic perivascular infiltrates (n=11), (2) dense...

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Identifiers

PMID: 28945625
DOI: 10.1097/PAS.0000000000000956

Genes

RHOA
IDH2
CXCL13
ICOS

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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