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Update on peripheral T-cell lymphomas with T-helper phenotype: Are there too many subtypes?

Seminars in diagnostic pathology - 1 Jan 2020

Piris Miguel A, Rodriguez-Pinilla Socorro M, Santonja Carlos, Betancor Isabel, Alonso-Alonso Ruth, Gru Alejandro A, Rodriguez Marta

Abstract excerpt

Follicular helper T (TFH) cells are the providers of T-cell help to B-cells in the development of germinal centers and for the generation of most class-switched antibodies. The markers most commonly associated with TFH activity are IL21, IL4, CD40L, BCL6, SAP, CXCR5/CXCL13, and ICOS. T-cell lymphoma genomic studies have shown that different T-cell lymphoma types express signatures typical for TFH cells, this...

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PMID: 31870687
DOI: 10.1053/j.semdp.2019.12.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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