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Article

Putative role of KIR3DL1/3DS1 alleles and HLA-Bw4 ligands with end stage renal disease and long term renal allograft survival.

Gene - 30 Dec 2017

Prakash Swayam, Sarangi Aditya Narayan, Alam Shahnawaz, Sonawane Avinash, Sharma Raj Kumar, Agrawal Suraksha

Abstract excerpt

BACKGROUND: Killer immunoglobulin receptors (KIR) are highly polymorphic in nature. KIR3DL1/3DS1 genes are known to affect HLA-B antigen binding affinity causing natural killer (NK) cell inhibition, which results into successful renal transplantation. In this study we have examined whether alleles of KIR3DL1/3DS1 play any role in changing the binding affinity with HLA-Bw4 antigen and if so then how are they...

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Source

Identifiers

PMID: 28942035
DOI: 10.1016/j.gene.2017.09.033

Variants

rs143159382

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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