Article
Structure of a SLC26 anion transporter STAS domain in complex with acyl carrier protein: implications for E. coli YchM in fatty acid metabolism.
Structure (London, England : 1993) - 10 Nov 2010
Babu Mohan, Greenblatt Jack F, Emili Andrew, Strynadka Natalie C J, Reithmeier Reinhart A F, Moraes Trevor F
Abstract excerpt
Escherichia coli YchM is a member of the SLC26 (SulP) family of anion transporters with an N-terminal membrane domain and a C-terminal cytoplasmic STAS domain. Mutations in human members of the SLC26 family, including their STAS domain, are linked to a number of inherited diseases. Herein, we describe the high-resolution crystal structure of the STAS domain from E. coli YchM isolated in complex with acyl-carrier...
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