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Association of human leukocyte antigen class I polymorphism with spontaneous clearance of hepatitis B surface antigen in Qidong Han population.

Clinical & developmental immunology - 1 Jan 2013

Miao Fengqin, Sun Hang, Pan Ning, Xu Jinhuan, Qiu Jie, Shen Yuqing, Xie Wei, Zhang Jianqiong

Abstract excerpt

AIM: To investigate whether HLA class I polymorphisms could influence the clearance of hepatitis B surface antigen (HBsAg) in Qidong Han population. METHODS: We genotyped HLA-A, -B, and -C loci of 448 individuals with HBV persistent infection and 140 persons with spontaneous clearance of HBsAg by polymerase chain reaction with sequencing based typing (PCR/SBT). All the individuals were unrelated males enrolled...

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Follow-Up Studies
Hepatitis B, Chronic
Hepatitis B Surface Antigens
Hepatitis B virus
Histocompatibility Antigens Class I

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PMID: 24324503
DOI: 10.1155/2013/145725
PMCID: PMC3845701

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