Article
Molecular evolution of hepatitis B vaccine escape variants in China, during 2000-2016.
Vaccine - 13 Oct 2017
Wang Jie, Qiu Jing, Zhu Yinwei, Zhou Hui, Yu Lugang, Ding Yi, Zhang Lige, Guo Zhirong, Dong Chen
Abstract excerpt
Hepatitis B vaccine escape variants are the main threat to hepatitis B virus (HBV) infection in vaccination era worldwide. With 215 genotype B HBV and 313 genotype C HBV vaccine escape variants isolated from China during 2000-2016, we reported that genotype B HBV vaccine escape strains diverged in ∼1997 (95% HPD; 1987-2005), while genotype C HBV vaccine escape strains diverged in ∼1976 (95% HPD; 1955-2003)....
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