Article
Analysis of sex hormone genes reveals gender differences in the genetic etiology of blood pressure salt sensitivity: the GenSalt study.
American journal of hypertension - 1 Feb 2013
Kelly Tanika N, Rebholz Casey M, Gu Dongfeng, Hixson James E, Rice Treva K, Cao Jie, Chen Jichun, Li Jianxin, Lu Fanghong, Ma Jixiang, Mu Jianjun, Whelton Paul K, He Jiang
Abstract excerpt
BACKGROUND: We examined the association between 799 single-nucleotide polymorphisms in 39 sex hormone genes and blood pressure (BP) responses to a dietary-sodium intervention. METHODS: A 7-day low-sodium feeding study (51.3 mmol sodium/day) followed by a 7-day high-sodium feeding study (307.8 mmol sodium/day) was conducted among 1,906 Han Chinese participants. Nine BP measurements were obtained at baseline and...
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