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Article

GATA3 regulates FLG and FLG2 expression in human primary keratinocytes

13 Sept 2017

Abstract excerpt

GATA3 is a transcription factor with an important role in atopic diseases because of its role in the differentiation of Th2 lymphocytes. Moreover, GATA3 is expressed in keratinocytes and has a role in keratinocyte differentiation and the establishment of the epidermal barrier. In this study, we investigated the role of GATA3 in keratinocytes in the context of epidermal barrier integrity under inflammatory skin...

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PMID: 28928464
DOI: 10.1038/s41598-017-10252-x

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