Article
Allele Age Under Non-Classical Assumptions is Clarified by an Exact Computational Markov Chain Approach.
Scientific reports - 19 Sept 2017
De Sanctis Bianca, Krukov Ivan, de Koning A P Jason
Abstract excerpt
Determination of the age of an allele based on its population frequency is a well-studied problem in population genetics, for which a variety of approximations have been proposed. We present a new result that, surprisingly, allows the expectation and variance of allele age to be computed exactly (within machine precision) for any finite absorbing Markov chain model in a matter of seconds. This approach makes none...
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