Article
The effect of recurrent mutation on the frequency spectrum of a segregating site and the age of an allele.
Theoretical population biology - 1 Sept 2011
Jenkins Paul A, Song Yun S
Abstract excerpt
The sample frequency spectrum of a segregating site is the probability distribution of a sample of alleles from a genetic locus, conditional on observing the sample to be polymorphic. This distribution is widely used in population genetic inferences, including statistical tests of neutrality in which a skew in the observed frequency spectrum across independent sites is taken as a signature of departure from...
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