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Article

Multi-azole-resistant strains of Cryptococcus neoformans var. grubii isolated from a FLZ-resistant strain by culturing in medium containing voriconazole.

Medical mycology - 1 Nov 2017

Kano Rui, Okubo Miki, Hasegawa Atsuhiko, Kamata Hiroshi

Abstract excerpt

A Cryptococcus neoformans var. grubii strain, NUBS14020, was the first fluconazole (FLZ)-resistant strain isolated from a feline cryptococcosis. Subsequent work demonstrated that multi-azole-resistant strains are readily isolated from FLZ-resistant strains by culturing in medium containing voriconazole (VRZ). The resulting clones were assessed for mutation and expression of known target genes, including the loci...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28927230
DOI: 10.1093/mmy/myw101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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