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Article

In vivo development of fluconazole resistance in serial Cryptococcus gattii isolates from a cat.

Medical mycology - 1 Jun 2017

Sykes Jane E, Hodge Greg, Singapuri Anil, Yang Mai Lee, Gelli Angie, Thompson George R

Abstract excerpt

Elevated fluconazole minimum inhibitory concentrations (MICs) are more frequently observed in Cryptococcus gattii compared to C. neoformans isolates; however, the development of in vivo resistance and the molecular mechanisms responsible have not been reported for this species. We report a case of Cryptococcus gattii (molecular type VGIII) that developed reduced susceptibility to fluconazole during therapy and...

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Identifiers

PMID: 28339594
DOI: 10.1093/mmy/myw104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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