Article
Automated MicroSPECT/MicroCT Image Analysis of the Mouse Thyroid Gland.
Thyroid : official journal of the American Thyroid Association - 1 Nov 2017
Cheng Peng, Hollingsworth Brynn, Scarberry Daniel, Shen Daniel H, Powell Kimerly, Smart Sean C, Beech John, Sheng Xiaochao, Kirschner Lawrence S, Menq Chia-Hsiang, Jhiang Sissy M
Abstract excerpt
BACKGROUND: The ability of thyroid follicular cells to take up iodine enables the use of radioactive iodine (RAI) for imaging and targeted killing of RAI-avid thyroid cancer following thyroidectomy. To facilitate identifying novel strategies to improve 131I therapeutic efficacy for patients with RAI refractory disease, it is desired to optimize image acquisition and analysis for preclinical mouse models of...
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