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Article

CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation

8 Nov 2020

Abstract excerpt

CRSP8 plays an important role in recruiting mediators to genes through direct interaction with various DNA-bound transactivators. In this study, we uncovered the unique function of CRSP8 in suppressing thyroid cancer differentiation and promoting thyroid cancer progression via targeting IKKα signaling. CRSP8 was highly expressed in human thyroid cancer cells and tissues, especially in anaplastic thyroid cancer...

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PMID: 33162555
DOI: 10.1038/s41418-020-00656-0

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