Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic rodent models of brain disorders: Perspectives on experimental approaches and therapeutic strategies.

American journal of medical genetics. Part C, Seminars in medical genetics - 1 Sept 2017

McGraw Christopher M, Ward Christopher S, Samaco Rodney C

Abstract excerpt

Neurobehavioral disorders comprised of neurodegenerative, neurodevelopmental, and psychiatric disorders together represent leading causes of morbidity and mortality. Despite significant academic research and industry efforts to elucidate the disease mechanisms operative in these disorders and to develop mechanism-based therapies, our understanding remains incomplete and our access to tractable therapeutic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Diseases
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Heredodegenerative Disorders, Nervous System

Share to Mental Disorders

Share to Neurodevelopmental Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 28910526
DOI: 10.1002/ajmg.c.31570
PMCID: PMC5659732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic rodent models of brain disorders: Perspectives on experimental approaches and therapeutic strategies.PMID 28910526Read ↗

Practical considerations of genetic rodent models for neurodegenerative diseases.Semantic proximity Read ↗

A critical overview of animal models of psychiatric disorders: challenges and perspectives.Semantic proximity Read ↗

From psychiatric disorders to animal models: a bidirectional and dimensional approach.Semantic proximity Read ↗

Emerging pharmacotherapies for neurodevelopmental disorders.Semantic proximity Read ↗

Behavioral Phenotyping Assays for Genetic Mouse Models of Neurodevelopmental, Neurodegenerative, and Psychiatric Disorders.Semantic proximity Read ↗

Animal models of neurodevelopmental disorders with behavioral phenotypes.Semantic proximity Read ↗

Animal models for neuropsychiatric disorders: prospects for circuit intervention.Semantic proximity Read ↗

Mouse mutagenesis and disease models for neuropsychiatric disorders.Semantic proximity Read ↗

Behavioral and neuroanatomical approaches in models of neurodevelopmental disorders: opportunities for translation.Semantic proximity Read ↗

The translational genetics of ADHD and related phenotypes in model organisms.Semantic proximity Read ↗

Impact of brain-behavior phenotypying of genetically-engineered mice on research of neuropsychiatric disorders.Semantic proximity Read ↗

Prioritizing the development of mouse models for childhood brain disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.