Article
Practical considerations of genetic rodent models for neurodegenerative diseases.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Geghman Kindiya, Li Chenjian
Abstract excerpt
In recent years, the rapid advances in human genetics have identified many genes that are responsible for inherited diseases. In the effort to understand pathogenic pathways and develop therapeutics, researchers have developed genetic animal models as critical tools for the purpose of neurodegenerative disease study. In this overview chapter, we do not intend to cover all the transgenic models for particular...
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