Article
Feasibility study of contralateral risk-reducing mastectomy with breast reconstruction for breast cancer patients with BRCA mutations in Japan.
Breast cancer (Tokyo, Japan) - 1 Sept 2018
Yoshimura Akiyo, Okumura Seiko, Sawaki Masataka, Hattori Masaya, Ishiguro Junko, Adachi Yayoi, Kotani Haruru, Gondo Naomi, Kataoka Ayumi, Iwase Madoka, Onishi Sakura, Sugino Kayoko, Terada Mitsuo, Horisawa Nanae, Mori Makiko, Takaiso Nobue, Hyodo Ikuo, Iwata Hiroji
Abstract excerpt
BACKGROUND: Contralateral risk-reducing mastectomy (CRRM) for breast cancer patients with BRCA mutations has been reported to not only reduce breast cancer incidence but also to improve survival. The National Comprehensive Cancer Network guidelines recommend providing CRRM to women with BRCA mutations who desire CRRM after risk-reduction counseling. However, in Japan, CRRM cannot be performed generally because it...
Topics
- Adult
- Breast Neoplasms
- Feasibility Studies
- Female
- Genes, BRCA1
- Genes, BRCA2
- Genetic Predisposition to Disease
- Humans
- Japan