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Article

Ataxia-Telangiectasia Mutated (ATM) Protein Signaling Participates in Development of Pulmonary Arterial Hypertension in Rats.

Medical science monitor : international medical journal of experimental and clinical research - 12 Sept 2017

Hu Fan, Liu Caijun, Liu Hanmin, Xie Liang, Yu Li

Abstract excerpt

BACKGROUND Previous studies revealed physiological and pathogenetic similarity between vascular smooth muscles cells with severe pulmonary arterial hypertension and tumors. The DNA damage response was found in both pulmonary arterial hypertension (PAH) cells and tumors. The ataxia-telangiectasia mutated proteins (ATM) pathway is considered an important factor in the DNA damage response of tumor formation, but its...

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Source

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Identifiers

PMID: 28894083
DOI: 10.12659/msm.906568
PMCID: PMC5606263

Genes

ATM
PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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