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Article

Associations of TGFBR1 and TGFBR2 gene polymorphisms with the risk of hypospadias: a case-control study in a Chinese population.

Bioscience reports - 31 Oct 2017

Han Xin-Rui, Wen Xin, Wang Shan, Hong Xiao-Wu, Fan Shao-Hua, Zhuang Juan, Wang Yong-Jian, Zhang Zi-Feng, Li Meng-Qiu, Hu Bin, Shan Qun, Sun Chun-Hui, Bao Ya-Xing, Lin Meng, He Tan, Wu Dong-Mei, Lu Jun, Zheng Yuan-Lin

Abstract excerpt

This case-control study investigated the association of transforming growth factor-β (TGF-β) receptor type I and II (TGFBR1 and TGFBR2) gene polymorphisms with the risk of hypospadias in a Chinese population. One hundred and sixty two patients suffering from hypospadias were enrolled as case group and 165 children who underwent circumcision were recruited as control group. Single nucleotide polymorphisms (SNPs)...

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Identifiers

PMID: 28894026
DOI: 10.1042/BSR20170713
PMCID: PMC5629700

Genes

TGFBR2
TGFBR1

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