Mutations of KIF14 cause primary microcephaly by impairing cytokinesis.

doi:10.1002/ana.25044

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Article

Mutations of KIF14 cause primary microcephaly by impairing cytokinesis.

Annals of neurology - 1 Oct 2017

Moawia Abubakar, Shaheen Ranad, Rasool Sajida, Waseem Syeda Seema, Ewida Nour, Budde Birgit, Kawalia Amit, Motameny Susanne, Khan Kamal, Fatima Ambrin, Jameel Muhammad, Ullah Farid, Akram Talia, Ali Zafar, Abdullah Uzma, Irshad Saba, Höhne Wolfgang, Noegel Angelika Anna, Al-Owain Mohammed, Hörtnagel Konstanze, Stöbe Petra, Baig Shahid Mahmood, Nürnberg Peter, Alkuraya Fowzan Sami, Hahn Andreas, Hussain Muhammad Sajid

Abstract excerpt

OBJECTIVE: Autosomal recessive primary microcephaly (MCPH) is a rare condition characterized by a reduced cerebral cortex accompanied with intellectual disability. Mutations in 17 genes have been shown to cause this phenotype. Recently, mutations in CIT, encoding CRIK (citron rho-interacting kinase)-a component of the central spindle matrix-were added. We aimed at identifying novel MCPH-associated genes and...

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Identifiers

PMID: 28892560
DOI: 10.1002/ana.25044

Genes

KIF14
CIT

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations of KIF14 cause primary microcephaly by impairing cytokinesis.PMID 28892560Read ↗

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