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Article

Molecular genetics of human primary microcephaly: an overview.

BMC medical genomics - 1 Jan 2015

Faheem Muhammad, Naseer Muhammad Imran, Rasool Mahmood, Chaudhary Adeel G, Kumosani Taha A, Ilyas Asad Muhammad, Pushparaj Peter, Ahmed Farid, Algahtani Hussain A, Al-Qahtani Mohammad H, Saleh Jamal Hasan

Abstract excerpt

Autosomal recessive primary microcephaly (MCPH) is a neurodevelopmental disorder that is characterised by microcephaly present at birth and non-progressive mental retardation. Microcephaly is the outcome of a smaller but architecturally normal brain; the cerebral cortex exhibits a significant decrease in size. MCPH is a neurogenic mitotic disorder, though affected patients demonstrate normal neuronal migration,...

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Source

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Identifiers

PMID: 25951892
DOI: 10.1186/1755-8794-8-S1-S4
PMCID: PMC4315316

Genes

ASPM
CDK6
MCPH1
PHC1
STIL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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