Article
Mutations of RNA splicing factors in hematological malignancies.
Cancer letters - 28 Nov 2017
Shukla Girish C, Singh Jagjit
Abstract excerpt
Systematic large-scale cancer genomic studies have produced numerous significant findings. These studies have not only revealed new cancer-promoting genes, but they also have identified cancer-promoting functions of previously known "housekeeping" genes. These studies have identified numerous mutations in genes which play a fundamental role in nuclear precursor mRNA splicing. Somatic mutations and copy number...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
