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X-linked polymorphisms in TLR7 and TLR8 genes are associated with protection against Chikungunya fever

1 Jan 2025

Abstract excerpt

BACKGROUND: Chikungunya virus (CHIKV) causes an infection that leads to the activation of the innate immune response, triggering receptor pathways such as toll-like receptors (TLRs). OBJECTIVE: The present study aimed to investigate the association of single nucleotide polymorphisms (SNPs) in genes encoding toll-like receptors 3, 7, and 8 and IRF5 in susceptibility to CHIKV infection and persistent joint pain....

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PMID: 40531670
DOI: 10.1590/0074-02760230224

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