Article
Exploring the interaction between Mycobacterium tuberculosis enolase and human plasminogen using computational methods and experimental techniques.
Journal of cellular biochemistry - 1 Feb 2018
Rahi Amit, Dhiman Alisha, Singh Damini, Lynn Andrew M, Rehan Mohd, Bhatnagar Rakesh
Abstract excerpt
Surface localized microbial enolases' binding with human plasminogen has been increasingly proven to have an important role in initial infection cycle of several human pathogens. Likewise, surface localized Mycobacterium tuberculosis (Mtb) enolase also binds to human plasminogen, and this interaction may entail crucial consequences for granuloma stability. The current study is the first attempt to explore the...
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