Article
Fructose-1,6-bisphosphate aldolase of Neisseria meningitidis binds human plasminogen via its C-terminal lysine residue.
MicrobiologyOpen - 1 Apr 2016
Shams Fariza, Oldfield Neil J, Lai Si Kei, Tunio Sarfraz A, Wooldridge Karl G, Turner David P J
Abstract excerpt
Neisseria meningitidis is a leading cause of fatal sepsis and meningitis worldwide. As for commensal species of human neisseriae, N. meningitidis inhabits the human nasopharynx and asymptomatic colonization is ubiquitous. Only rarely does the organism invade and survive in the bloodstream leading to disease. Moonlighting proteins perform two or more autonomous, often dissimilar, functions using a single...
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