Article
Lack of association of CASC8 rs1447295 with colorectal cancer in Iranian population: A multicenter case-control study.
Gene - 15 Nov 2017
Haerian Monir Sadat, Haerian Batoul Sadat, Molanaei Saadat, Kosari Farid, Sabeti Shahram, Bidari-Zerehpoosh Farahnaz, Abdolali Ebrahim
Abstract excerpt
Several studies reported the potential role of the rs1447295 polymorphism in susceptibility to cancer. This variant located in the cancer susceptibility candidate 8 (CASC8) is a long noncoding RNA (lnRNA) gene and does not code protein. LnRNA transcripts play a potential regulatory role in the expression of key genes involved in multiple cellular pathways, including cell cycle, pluripotency, and immune response....
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