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Article

Myotome adaptability confers developmental robustness to somitic myogenesis in response to fibre number alteration.

Developmental biology - 15 Nov 2017

Roy Shukolpa D, Williams Victoria C, Pipalia Tapan G, Li Kuoyu, Hammond Christina L, Knappe Stefanie, Knight Robert D, Hughes Simon M

Abstract excerpt

Balancing the number of stem cells and their progeny is crucial for tissue development and repair. Here we examine how cell numbers and overall muscle size are tightly regulated during zebrafish somitic muscle development. Muscle stem/precursor cell (MPCs) expressing Pax7 are initially located in the dermomyotome (DM) external cell layer, adopt a highly stereotypical distribution and thereafter a proportion of...

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Identifiers

PMID: 28887016
DOI: 10.1016/j.ydbio.2017.08.029
PMCID: PMC5667637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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