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Article

Epigenetic regulation of inflammation in localized aggressive periodontitis

2 Sept 2017

Abstract excerpt

We have previously demonstrated a Toll-like receptor (TLR)-mediated hyper-responsive phenotype in our cohort of localized aggressive periodontitis (LAP) individuals. However, mechanisms related to this phenotype are still not clear in the literature. The objective of this cross-sectional study is to examine the role of epigenetic regulation, specifically DNA methylation status of genes in the TLR pathway in this...

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PMID: 28883894
DOI: 10.1186/s13148-017-0385-8

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