Article
Genetic disorders associated with ATP binding cassette cholesterol transporters.
Molecular genetics and metabolism - 1 Jan 2000
Burris Thomas P, Eacho Patrick I, Cao Guoqing
Abstract excerpt
Coronary artery disease is the most prevalent form of mortality and morbidity in Western countries. Studies in the last several decades have identified high LDL cholesterol and low HDL cholesterol as major risk factors leading to the disease. Human genetic studies have provided significant insight into the regulation of lipoprotein metabolism. In the last several years, the genes associated with several rare...
Topics
- ATP Binding Cassette Transporter 1
- ATP Binding Cassette Transporter, Subfamily G, Member 5
- ATP Binding Cassette Transporter, Subfamily G, Member 8
- ATP-Binding Cassette Transporters
- Animals
- Cholesterol
- DNA-Binding Proteins
- Homeostasis
- Humans
- Lipid Metabolism, Inborn Errors
- Lipoproteins
- Lipoproteins, HDL
- Liver X Receptors