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IL-1β haplotype influences the effect of NOx exposure on gestational age in the South African MACE birth cohort.

Human & experimental toxicology - 1 Jul 2018

Nansook P, Naidoo R N, Ramkaran P, Phulukdaree A, Muttoo S, Asharam K, Chuturgoon A A

Abstract excerpt

OBJECTIVE: Cytokines, molecules within the immune system that affect either a pro- or anti-inflammatory response, have previously been shown to influence birth outcomes. The maternal cytokine gene-environment interactions are thought to alter their expression, potentially influencing susceptibility to adverse birth outcomes. The aim of this study was to determine the association between the maternal...

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PMID: 28875725
DOI: 10.1177/0960327117728386

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