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Article

RPE65 has an additional function as the lutein to <i>meso</i> -zeaxanthin isomerase in the vertebrate eye

5 Sept 2017

Abstract excerpt

Significance Carotenoids are plant-derived pigment molecules that cannot be synthesized de novo by higher organisms. These physiologically relevant compounds function as potent antioxidants and light screening compounds, and their supplementation has been shown to ameliorate the progression of such diseases as age-related macular degeneration. Hundreds of carotenoids are present in the plant world, but the...

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PMID: 28874556
DOI: 10.1073/pnas.1706332114

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